PTPN22 as a novel therapeutic target: a key intracellular checkpoint for NK cell therapy
Abstract Background PTPN22, a protein tyrosine phosphatase (PTP) family member, has recently emerged as an intracellular regulator in adaptive immune cells. However, its function in natural killer (NK) cells remains unclear despite its high expression in innate immune cells. Methods We analyzed single-cell RNA-sequenci...
Tung Nguyen Thanh Uong, Meesun Yoon, Nhat Phuoc Nguong Minh Nguyen et al.
· Journal for ImmunoTherapy of... · 0 citations