#gene editing
Sep 2026
Non-invasive control of gene editing in vivo by photoswitchable Cas12f and focused ultrasound.
This study engineer compact photoswitchable Cas12f (psCas12f) proteins that are co-deliverable with their single guide RNA (sgRNA) in a single AAV particle, enabling precise spatiotemporal control in vivo.
Daesun Song, Marigold G. Malinao, Xiang Wu et al.
· Cell · 0 citations