Hyaluronidase-Responsive MSN-HA Coatings for Infection-Triggered Antibiotic Delivery on Titanium Surfaces.
The developed coating combines anti-adhesive surface properties with controlled, infection-triggered antibiotic release, limiting unnecessary drug exposure while improving localized antibacterial activity, highlighting the potential of HA-coated MSN coatings as smart implant surface modifications for reducing implant-associated infections and biofilm formation.