Review
Sep 2026
Therapeutic Strategies Targeting TREM2 for Alzheimer's Disease: Current Advances and Future Perspectives.
TREM2 remains a promising but context-sensitive therapeutic target that functions within a context-dependent framework in which gene dosage, disease stage, pathological substrate, microglial state, and activation duration jointly determine protective or maladaptive outcomes.
Yi-Xiang Yu, Yan-Ji Xu, Mei-Hua Xu
· Current Neuropharmacology · 0 citations