The integrated biocomputing and metabolic locking systems not only alleviate production degeneration but also enable non-degenerative adaptation of toxic terpene synthesis, allowing interrogation of evolutionary shifts for further metabolic optimisation.
Ze-Yu Lu, Craig P. Barry, Masahiro Tominaga et al.· bioRxiv· 0 citations
Overall, transposon-based tools represent a valuable and underexplored avenue to accelerate genome engineering and strain development in yeasts and filamentous fungi.
Bing-Yin Peng, Masahiro Tominaga, Cheng-Qiang Wang et al.· Yeast· 1 citation
Recent advances and future potential in engineering methylotrophic yeasts for food protein production, with particular focus on Komagataella phaffii are reviewed, addressing the dual goals of improving both yield and quality.
Bing-Yin Peng, Masahiro Tominaga, Jun Ishii et al.· Metabolic Engineering· 0 citations
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