Impact of Sphingolipid Metabolizing Enzyme β-Galactosylceramidase on Mitochondrial Sphingolipid Profile and Energetic Metabolism in Human Melanoma Cells
Background/Objectives: Mitochondrial plasticity, reflected by the capacity of cancer cells to shift between oxidative phosphorylation and glycolytic metabolism in response to genetic alterations and changes in the tumor microenvironment, represents a key feature of melanoma progression. Sphingolipids contribute to the...