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Author

Mahtab Ahmad Khan

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Review Aug 2026

Rebalancing α-Synuclein Clearance: Novel Therapeutic Frontiers in Parkinson’s Disease

It is proposed that a systems-level approach can be taken where PD is understood as a disease characterized by the imbalance in proteostasis, and potential treatment modalities include small molecules targeting lysosome function, CMA enhancers, gene therapy, and antibodies against extracellular α-synuclein.

Maryam Jabeen, Huma Hameed, Syed Muhammad Ahmad et al. · 0 citations

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