Author

M. Wolkers

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Open access Sep 2026

Proximity labeling puts ZFP36L1 as central hub for posttranscriptional regulation networks in T cells

RNA binding proteins (RBPs) are key regulators of controlling the proteome remodeling during T-cell activation. Using proximity labeling, we present a comprehensive interactome map of the RBP ZFP36L1, demonstrating the versatility of interactions and their possible functioning during T-cell activation.

Anouk P. Jurgens, Branka Popović, Floris P. J. van Alphen et al. · Life Science Alliance · 0 citations

Open access Aug 2026

Proteomics of human cancer-associated T cells identifies regulators of T cell functionality

Integrated multi-omic profiling of human tumor-infiltrating T cells reveals cell-intrinsic regulators of T cell dysfunction that are missed by transcriptomic analyses alone, highlighting an additional layer of regulatory control.

Kaspar Bresser, Zan Hozjan, N. Servaas et al. · bioRxiv · 0 citations