Author

M. Pokusa

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Open access Sep 2026

Bardoxolone methyl induces mitochondrial dysfunction, activation of the cytosolic stress response, and increased chaperone capacity in SH-SY5Y cells. Focus on mitochondrial protease LONP1.

The results indicate that mitochondrial dysfunction, activation of cytosolic stress response, and an increase in chaperone capacity elicited by CDDO-Me could be attributed to CDDO-Me's ability to inhibit LONP1 protease.

Ľuboš Hudák, A. Evinova, Monika Liskova et al. · General Physiology and Bioph... · 0 citations

Open access Aug 2026

Derivation of a new induced pluripotent stem cell line ORIONi004-A for modelling Duchenne muscular dystrophy.

Peripheral blood was used as source for primary cells and subsequently reprogrammed into induced pluripotent stem cells with synthetic Sendai vector, which showed the expression of pluripotency factors and the ability to differentiate into all three germ layers.

Dominika Hajduchova, Stanislava Suroviaková, S. Mersakova et al. · Stem Cell Research · 0 citations