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M. Cherukara

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Review Sep 2026

Strategies for Deploying AI Agents in Production at Scientific User Facilities

Agentic artificial intelligence (AI) is moving beyond research demonstrations toward production use at scientific user facilities, including light sources, neutron sources, nanoscience centers, and autonomous laboratories. Its scientific value extends beyond increasing throughput. Agents can perform repeatable tasks in...

Ming Du, Xiang-Yu Yin, Michael H. Prince et al. · 0 citations
Preprint Jul 2026

An End-to-End Differentiable Forward Model for High-Energy Diffraction Microscopy

High-Energy Diffraction Microscopy (HEDM) recovers crystallographic orientation, strain, and grain position from rotating-crystal X-ray diffraction patterns. Existing forward models in far-field (FF), near-field (NF), and point-focused (pf) HEDM are not differentiable, which forecloses gradient-based joint parameter re...

Hemant Sharma, Nina Andrejevic, Simon Zhang et al. · 1 citation
Preprint Aug 2026

Artifact-centered Claim-aware Observability for Autonomous Scientific Agents

This work argues that autonomous scientific systems should emit portable, claim-aware artifact lineage as a minimum audit layer, and proposes a compact observability profile organized around individuals, operators, fitness records, lineage, archives, runs, streams, and steering commands.

Xiang-Yu Yin, Ming Du, Michael H. Prince et al. · 1 citation
Review Aug 2026

Acquisition Geometry-Assisted Whole-Group Localization of X-ray Fluorescence Maps in Optical Microscopy Images

X-ray fluorescence (XRF) microscopy maps elemental distributions, while optical microscopy can provide complementary morphological context. Localizing XRF fields of view (FOVs) in optical images is difficult because the two modalities differ in contrast mechanism and resolution. Most current workflows place each XRF ti...

Xiang-Yu Yin, T. Paunesku, Letonia Copeland-Hardin et al. · 0 citations
#small language model Preprint Aug 2026

XRF-to-Optical Field-of-View Localization with Vision Language Models

This paper evaluates training-free vision language model (VLM) localization on two datasets representing same-section high-correspondence and adjacent-section low-correspondence imaging and tests unconstrained and metadata-constrained search and VLMs with geometric controls, classical template matching, and two alterna...

Xiang-Yu Yin, T. Paunesku, Letonia Copeland-Hardin et al. · 0 citations

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