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Review Sep 2026

Phosphatidylethanolamine-mediated metabolic membrane remodeling in obesity-associated Alzheimer’s disease: mechanisms, neuroimmune crosstalk, and therapeutic potential

This review critically examines the molecular and cellular mechanisms underlying PE-mediated adipose–brain crosstalk in obesity-associated Alzheimer’s disease, with emphasis on mitochondrial dysfunction, blood–brain barrier disruption, ferroptosis, membrane remodeling, and microglial activation.

Mumtaz Ahmad, Moh Aijaz, Mohamamd Anas Ansari et al. · 0 citations
Aug 2026

Erucic acid arbitrates neuroprotection in streptozotocin-induced memory deficit via improving oxidative stress/neuroinflammatory indicators/cholinergic activity in rodents.

BACKGROUND Erucic acid (EA), a monounsaturated omega-9 fatty acid derived from Raphanus sativus L. seeds, has antioxidant and anti-inflammatory properties. This study investigated its neuroprotective effects against streptozotocin (STZ)-induced diabetes-associated cognitive dysfunction in rats. METHODS Male Wistar ra...

N. Sayyed, M. Afzal, Misbahudin Rafeeq et al. · 0 citations

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