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Author

Lu Ding

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Review Aug 2026

CAR-T cell therapy for autoimmune diseases: from immune suppression to immune resetting.

A review of immunopathogenesis and therapeutic gaps in representative autoimmune diseases, compares CAR-T applications in malignancies and autoimmunity, and evaluates emerging response endpoints, target-selection strategies, and safety considerations in autoimmune settings suggests CAR-T therapy offers a potential stra...

Mengting Zhang, Lianfeng Zhao, Tianyu Chen et al. · 0 citations
#gene editing Review Aug 2026

Universal CAR-T cell therapy: mechanisms and evasion strategies of bidirectional immune rejection.

This review systematically delineates the mechanisms underlying bidirectional immune rejection and comprehensively summarizes state-of-the-art mitigation strategies and highlights the development of alternative, inherently hypoimmunogenic cell sources as a fundamental approach to circumventing these immunological barri...

Lu Ding, Lianfeng Zhao, Mengting Zhang et al. · 0 citations

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