Author

Lie-Chen Ji

2 papers indexed here

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Open access Sep 2026

Cofilin/RhoA and CREB synergistically promote invasion and migration of polyploid giant cancer cells in colorectal cancer

Colorectal cancer (CRC) is associated with high mortality and poor survival. Polyploid giant cancer cells (PGCCs) are a subset of cancer cells that drive tumor initiation and progression. In this study, high-concentration CoCl₂ treatment was used to induce Hct116 and LoVo cells to form PGCCs with daughter cells (PDCs),...

Yi-Di Ning, Kai Liu, Jing Xu et al. · Journal of Cancer · 0 citations

Open access Aug 2026

CCT2 Promotes Immune Escape in Colorectal Cancer by Regulating the JAK1‐STAT3‐PD‐L1 Axis

This study explored the molecular mechanisms underlying CRC immune evasion as well as the therapeutic effects of immune checkpoint inhibitors in microsatellite‐stable/proficient mismatch repair CRC.

Li-Qiang Gu, Shao-Fei Li, Yi-Chao Tang et al. · Journal of Gastroenterology... · 0 citations