Author

Liangji Zhou

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Open access Sep 2026

Hierarchical Phase Transitions in Bayesian Flow Networks Enable Training-Free Molecular Design

Bayesian flow networks (BFNs) jointly model atomic coordinates and atom types for structure-based drug design, but their generative dynamics remain poorly understood. We show that the two channels resolve on different terms: atom types pass through a sharp commitment transition at tc1, whereas coordinate precision im...

Liang-Ji Zhou, Yuan-Qiu Chen, Tong-Tong Chen et al. · Journal of Chemical Informat... · 0 citations

#gene editing Open access Aug 2026

Programmable RNA targeting with clustered regularly interspaced short palindromic repeats (CRISPR) effector Cas7-11 in zebrafish embryos and mammalian cells

Findings establish Cas7-11 as a precise and efficient RNA knockdown tool for functional studies in embryonic development and stem cell biology, providing a versatile alternative to DNA-based gene-editing approaches.

Huan Yan, Imtiaz Ul Hassan, Kai Yan et al. · Cell & Bioscience · 0 citations