ABSTRACT African swine fever (ASF), caused by African swine fever virus (ASFV), is a devastating viral disease in domestic pigs and wild boar. ASFV is a large DNA virus whose capsid assembly takes place within perinuclear viral factories (VFs). Accumulating evidence has demonstrated that reticulophagy confers antiviral...
Rui Luo, Jing Zhang, Ruojia Huang et al.· Advancement of science· 0 citations
It is demonstrated that needle-free delivery of rPRVTJ-UL44-E2 confers complete protection against lethal CSFV challenge in pigs via needle-free immunization.
Ruojia Huang, Qiang Yang, Cao-Yuan Ma et al.· Vaccines· 0 citations
Background/Objectives: Pseudorabies virus (PRV) variant strains have caused widespread outbreaks in China since 2011, and currently available vaccines provide suboptimal protection. Glycoprotein D (gD), the principal target of virus-neutralizing antibodies, represents a promising antigen for subunit vaccine development...
Caoyuan Ma, Jia Li, Xin Song et al.· Vaccines· 0 citations
The generation of a WSL-Cas9 monoclonal cell line with high CRISPR/Cas9 editing efficiency, stable proliferation, and permissiveness for robust ASFV replication is reported, providing a reliable platform for future genome-wide functional screening to systematically identify host factors governing ASFV entry.
Meng Yao, Tianlong Li, Bin Sun et al.· Sheng wu gong cheng xue bao...· 0 citations
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