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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Li-Ping Peng

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Open access Aug 2026

Identification of a Conserved Linear Epitope in SARS-CoV-2 Nucleocapsid Protein Recognized by Monoclonal Antibody N179

This motif may serve as a reference for the selection and evaluation of diagnostic antibodies targeting conserved regions of the SARS-CoV-2 N protein and show that this sequence is conserved among the representative SARS-CoV-2 lineages analyzed.

Zhoujun Su, Junhao Guo, Ning Li et al. · 0 citations
Open access Jul 2026

A Variant-Resistant Linear Epitope in the SARS-CoV-2 Nucleocapsid Protein for Antigen Detection

The results provide an epitope-level explanation for the sustained diagnostic reliability of the mAb N179-based assay against emerging variants, clarify the molecular basis for its lack of cross-reactivity, and may inform the rational design of SARS-CoV-2 diagnostics targeting conserved, mutation-resistant epitopes.

Zhoujun Su, Junhao Guo, He-Feng Zhou et al. · 0 citations

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