A Toolbox for Binary and Rheostat-like Modulation of TOX Expression via Genome and Epigenome Editing in Primary Human T cells
These studies show that a complete TOX knockout or silencing has no effect on exhaustion marker expression levels or the transcriptome in repeat-anti-CD3/anti-CD28-stimulated primary human T cells in vitro.
Elaine V. Schanzer, Katharine F. Vostrejs, Alexandra N. Kurciska et al.
· bioRxiv · 0 citations