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Author

Kai-Cheng Wan

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2 papers indexed here

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Oct 2026

Sodium oxamate-functionalized microspheres alleviate Intervertebral disc degeneration by inhibiting excessive glycolysis in nucleus pulposus cells.

It is demonstrated that glycolytic reprogramming via SO synergizes potently with TGF-β3 to mitigate IVDD progression, and that the S-T@GM microsphere platform represents a promising integrative strategy that simultaneously targets metabolic dysfunction and impaired regeneration for effective intervertebral disc repair.

Mu-Nan Guo, Zhuang Zhu, Han-Cheng Shi et al. · 0 citations
Open access Aug 2026

Extracellular Matrix-Mimicking Dual-Network Hydrogel With Microenvironment Remodeling to Enhance Vascularized Skeletal Muscle Regeneration Following Volumetric Muscle Loss

Background: Volumetric muscle loss (VML) significantly impairs the inherent regenerative ability of skeletal muscle, causing dysfunction and scar tissue formation. Current treatments are limited to functional muscle transplantation, posing many complications and incomplete functional recovery. Methods: To simulate the...

Han-Chen Liu, Ji-Bai Tao, Feng-Cheng Chu et al. · 0 citations

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