Potency, off-target analysis, and comparability in vivo gene-edited therapy development
The guide RNA is a drug substance or a critical component with its own manufacturing requirement. It is not just a reagent and should not be treated as such. Abi Pinchbeck, Commissioning Editor, Cell & Gene Therapy Insights, speaks with Kok-Seong Lim, Principal, Eight Crest Strategies, about the analytical characteriza...