Author

K. Gokulakrishnan

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Sep 2026

Epigenome-Wide Placental Methylation Landscapes in Relation to Antenatal Depressive Symptoms.

Preliminary evidence of DNA methylation signatures linked to potential candidate genes and biological pathways that may be relevant to ADS are provided, supporting the need for validation in larger independent cohorts and functional experimental studies.

C. Thirumoorthy, Sree Sankar Darveekran Nair, M. Deepa et al. · Neurochemistry International · 0 citations

Review 2026

Epigenetic clues: Predicting maternal depression through DNA methylation.

DNA methylation represents a promising avenue for understanding the biological underpinnings of PND and developing robust biomarkers for risk prediction and personalized care, and integrating genetic, epigenetic, and environmental data through multi-omics approaches may enhance predictive accuracy and improve early int...

Varghese Merin Jerusha, C. Thirumoorthy, K. Gokulakrishnan · Methods in Enzymology · 0 citations

Jul 2026

Apo and substrate-bound dihydropteroate synthase crystal structures from Thermus thermophilus HB8.

High-resolution crystal structures of Thermus thermophilus HB8 DHPS and homologs from Escherichia coli and Mycobacterium tuberculosis highlight conserved catalytic features, as well as variable loop conformations and phosphate-binding residues that may contribute to differential sulfonamide sensitivity.

Amulya Ramakrishna, Archanalakshmi Kambaru, K. Gokulakrishnan et al. · European Biophysics Journal · 0 citations