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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Jotiram Salunkhe

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3 papers indexed here

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Review Sep 2026

Neuroprotective Potential of Phytochemicals: Exploration of Molecular Mechanisms in Neurodegeneration.

Neurodegeneration is a progressive loss of neuronal structure and function. Oxidative stress, neuroinflammation, mitochondrial dysfunction, excitotoxicity, and abnormal protein misfolding disrupt neural homeostasis leading to neurodegeneration. Phytochemicals have been used in the treatment of several diseases in the p...

Jotiram Salunkhe, Dr. Vinod Ugale, Prasad Kulkarni · 0 citations
Review Sep 2026

UPS-mediated P-glycoprotein regulation in Alzheimer’s disease: pharmacological implications for the amyloid pathology

Multiple factors associated with the AD are discussed, such as Aβ, oxidative stress, and inflammatory signaling, contributing to the phosphorylation, ubiquitination, internalization, and degradation of P-gp, which results in impaired transporter function and a compromised integrity of the BBB.

A. Joshi, Jotiram Salunkhe, Dr. Vinod Ugale · 0 citations
Review Open access Aug 2026

Ferroptosis and NMDA Receptor Activity in Alzheimer's Disease: Implications for Amyloid Pathology and P‐Glycoprotein Regulation

The review elucidates the molecular mechanisms linking ferroptosis and NMDA receptor overactivation and their impact on P‐gp‐mediated Aβ transport in the AD, providing integrated mechanisms and harnessing their potential for AD therapeutics.

Jotiram Salunkhe, Dr. Vinod Ugale · 0 citations

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