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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Jinmyoung Joo

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Open access Sep 2026

Structure-based analysis reveals a hydrophobic pocket governing P2Y12 receptor agonist potency and selectivity.

Agonist of the ADP-activated P2Y12 receptor modulate platelet aggregation and microglial function, yet the structural basis of their potency and selectivity remains unclear. Using recent active-state cryo-EM structures of P2Y12 and P2Y1 receptors, we applied an integrated modelling approach to revisit a structurally un...

Matteo Pavan, Jih-Yun Lee, John C. Hancock et al. · 0 citations
Review Open access Aug 2026

Integrating delivery systems and microenvironmental cues to accelerate clinical translation of cardiac reprogramming

Innovations in pericardial delivery systems and optimized manufacturing protocols now pave the way for future clinical translation of direct cardiac reprogramming strategies, which could redefine heart failure therapy.

Boram Son, Gwang Yeol Park, Ildoo Jeong et al. · 0 citations

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