Systematic Dissection of Key Driver Perturbation Signatures in Single Cells via ECCITE-seq.
An ECCITE-seq framework is described to characterize the transcriptomic consequences of perturbing multiple neuronal key driver genes associated with Alzheimer's disease (AD) in human-induced pluripotent stem cell (hiPSC)-derived neurons and allows for the assessment of the regulatory impact of candidate genes implicat...
Jing-Long Zhang, K. Brennand, Bin Zhang et al.
· Methods in molecular biology · 0 citations