Author

Jin-Xiu Li

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Review Sep 2026

Generation of eight-cell embryo-like cells from human pluripotent stem cells.

The approach provides a valuable model for studying human early embryogenesis, particularly the molecular events surrounding ZGA, and is expected that an individual with ~1 year of experience working with human PSC culture would be able to carry out this protocol.

Md. Abdul Mazid, Yun-Pan Li, Min-Die Zhao et al. · Nature Protocols · 0 citations

#protein folding Open access Sep 2026

“Sex-divergent responses to microglial depletion suggest distinct regulatory dependencies in the aged brain”

Sexual dimorphic responses to microglial depletion via CSF1R inhibition via CSF1R inhibition are characterized and candidate post-transcriptional mechanisms warranting further investigation are identified.

Amila Beganovic, M. Flotho, Jin-Xiu Li et al. · bioRxiv · 0 citations

Aug 2026

Multimodal brain cell atlas across the adult macaque lifespan.

A comprehensive transcriptomic and chromatin accessibility atlas of 8 brain regions of 23 female cynomolgus macaques spanning the adult lifespan, including exceptionally old individuals establishes a foundational framework for understanding the cellular and regulatory architecture of primate brain aging and its links t...

Xiao Zhang, Guang-Shun Lai, Xiang-Yu Guo et al. · Cell · 0 citations