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Author

Jie Qiao

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#reinforcement learning Open access Sep 2026

AI-Guided Multi-Objective Engineering of Glucoamylase Enables Acidification-Free Starch Saccharification

An artificial intelligence-guided strategy to simultaneously improve the thermostability, pH tolerance, and catalytic activity of glucoamylase from Penicillium oxalicum (PoGA) and folding energy guided recombination to achieve simultaneous multi property optimization is developed.

Jie Qiao, Xiao-Rui Ma, Yi-Bo Song et al. · 0 citations
Jul 2026

Overcoming catalytic barriers to reprogram acyltransferases for bis(2-hydroxyethyl) terephthalate hydrolysis.

The extensive use of polyethylene terephthalate (PET) has resulted in severe environmental pollution and ecological stress. Despite advances in PET recycling, current processes struggle to achieve high product value, as the complete conversion to terephthalic acid remains energetically demanding and economically ineffi...

Jie Qiao, Yibo Song, Nan Zhao et al. · 0 citations

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