Author

Jia-Rong He

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Open access Sep 2026

A multi-epitope vaccine targeting Mycoplasma pneumoniae P1 adhesin and CARDS toxin confers synergistic protection by adhesion inhibition and toxin neutralization

Background Mycoplasma pneumoniae (Mp) remains a major cause of community-acquired pneumonia in children and adolescents, and no vaccine against this pathogen is currently available. This study designed and evaluated P1Tx, a novel multi-epitope vaccine candidate derived from the immunodominant regions of the P1 adhesin...

Peng-Xiao Feng, Rui Hu, Huan-Bing Long et al. · Frontiers in Immunology · 0 citations

Open access Aug 2026

Integrated population-based evidence, network toxicology, single-cell profiling, and in vitro studies elucidate mechanisms connecting PAHs to stroke.

It is suggested that 2-NAP may represent an important contributor linking PAH exposure to stroke and that LAMP2-associated pathways may participate in PAH-related cerebrovascular injury.

Jian Cui, Wen-Jie Xu, Jia-Rong He et al. · Ecotoxicology and Environmen... · 0 citations

Aug 2026

WNK4 restrains endometrial cancer progression by reprogramming macrophage polarization toward an M1-like phenotype

WNK4 acts as an immune-relevant suppressor in endometrial cancer, partly by limiting M2-like polarization and weakening macrophage-driven tumor support, partly by limiting M2-like polarization and weakening macrophage-driven tumor support.

Jia-Rong He, Tian Zhang, Menglan Xiong et al. · Molecular Biology Reports · 0 citations