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Author

Jia-Le Zhou

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Preprint Aug 2026

Test-Time Adaptation for ECG Classification via SQI-Gated Self-Training and Beat-Rhythm Consistency

Deep learning models for electrocardiogram (ECG) classification often suffer from significant performance degradation when deployed in unseen domains due to shifts in acquisition devices and patient populations. Test-time adaptation (TTA) offers a practical solution by adapting models using only unlabeled data at infer...

Wen-Han Jiang, Zhi-Peng Deng, Jia-Le Zhou et al. · 0 citations
Book Open access Aug 2026

PRIME: A Pretrained Representation-Induced Model for 3D Molecules in De Novo Binder Design

Semantics-Preserving Exploratory Sampling (SPES), which integrates Graph Laplacian Spectral Noise to respect chain connectivity and Conditional Freedom Modulation to dynamically balance exploration with fidelity, enables diversity-enhanced generation without sacrificing geometric validity under the reported structural...

Zhihua Tian, Jiale Zhou, Rubo Wang et al. · 0 citations

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