Engineering strategies to address immune and delivery barriers in pancreatic ductal adenocarcinoma: a barrier-matched translational framework
This review evaluates oncolytic virotherapy, gene-editing technologies, engineered immune-cell therapies, nanotechnology-enabled delivery systems, and artificial intelligence-assisted precision oncology according to the PDAC barriers they are intended to address and the maturity of the supporting evidence.
Yang Li, Yu Li, Jia Fan et al.
· Frontiers in Immunology · 0 citations