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Author

J. Soucy

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3 papers indexed here

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Open access Aug 2026

Network-level functional connectivity is associated with longitudinal tau accumulation and amyloid-dependent cognitive decline in preclinical Alzheimer’s disease

Lower static connectivity across multiple large-scale networks was associated with faster longitudinal tau accumulation and, selectively in individuals with elevated amyloid burden, with accelerated cognitive decline, and these associations were not observed for time-varying connectivity.

Mohammadali Javanray, Jonathan Gallego-Rudolf, Y. Yakoub et al. · 0 citations
Open access Sep 2026

HIPPOCAMPAL TAU-RELATED SIGNAL INDEXES HYPEREXCITABILITY AND NREM SLEEP–MEMORY DYSFUNCTION IN TEMPORAL LOBE EPILEPSY

It is suggested that hippocampal 18F-MK6240 uptake may represent a candidate marker of circuit vulnerability associated with NREM sleep-memory dysfunction in TLE, warranting validation in larger longitudinal studies.

Thaera Arafat, Katharina Schiller, J. Lam et al. · 0 citations
Open access Aug 2026

Differential associations of tau extent and load with brain metabolic and cognitive dysfunction in Alzheimer's disease

Summary Background Reduced [18F]Fluorodeoxyglucose ([18F]FDG)-PET uptake is a core imaging feature of Alzheimer's disease (AD). While tau load correlates with this metabolic signature, it remains unclear whether the spatial extent of tauopathy (SEOT) more accurately explains brain glucose hypometabolic patterns. Here,...

Arthur C. Macedo, Lydia Trudel, S. A. Hosseini et al. · 1 citation

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