Author

J. M. Ragle

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Open access Sep 2026

Characterizing the Role of Tau Tubulin Kinase 8.1 and 8.2 in C. elegans Spermatozoan Motility.

Cell motility is essential for processes such as immune responses, wound healing, and fertilization. Caenorhabditis elegans is an excellent model for studying sperm motility, due to the worm's transparency and high sperm production. C. elegans amoeboid sperm move by extending and retracting pseudopods, which are powere...

Jenna K. Jablonski, Olivia D. Warren, Elena B. Benson et al. · Developmental Biology · 0 citations

#gene editing Open access Oct 2026

A systematic fluorescently tagged protein toolkit for dissecting apical extracellular matrix patterning in C. elegans.

Barrier epithelia are shielded from the external environment by their apical extracellular matrices (aECMs). The molecular complexity of aECMs has challenged understanding of their organization in vivo. To define the molecular architecture of a model aECM we generated a toolkit of 105 fluorescently tagged aECM componen...

J. M. Ragle, Murugesan Pooranachithra, Guinevere A. Ashley et al. · PLoS Biology · 0 citations

Sep 2026

An F2A sequence permits correct localization of a secreted and a nuclear localized reporter in C. elegans

These data provide a configuration for driving nuclear and secreted proteins from a single-copy transgene and indicate that downstream secreted proteins could be correctly directed to the secretory pathway.

J. M. Ragle, Guinevere A. Ashley, Jordan D. Ward · microPublication Biology · 0 citations