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Author

J. L. dos Santos

3 papers indexed here

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#gene editing Review Open access Aug 2026

Epigenetic strategies for fetal hemoglobin induction in sickle cell disease.

This review discusses medicinal chemistry approaches primarily targeting HDAC1/2, LSD1, and DNMT1, with emphasis on inhibitor classes, binding mechanisms, structural features, preclinical evidence, and translational limitations, and how a better understanding of γ-globin repression may guide the development of safer an...

Mateus Mello de Souza, A. R. Pavan, Victor Gabriel de Faria Pastre et al. · 0 citations
Review Open access Sep 2026

Insights into the use of artificial intelligence in the drug discovery and delivery of nanosystems for the treatment of infectious diseases and neoplasms.

The convergence of AI and nanotechnology is revolutionizing healthcare by providing more accurate diagnostics, tailored treatments, and improved safety evaluations, and AI-driven models enhance drug discovery, optimize delivery systems, and strengthen toxicological assessments.

Vinicius Martinho Borges Cardoso, Camila Rodrigues Santana, Giovanna Justino Momente et al. · 0 citations

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