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J. Hultquist

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Open access Aug 2026

APOBEC3G Splicing Defects in Nonhuman Primate Models Result in Disparate Viral Mutational Profiles Relative to Humans

It is reported that APOBEC3G (A3G), a potent antiviral restriction factor and the major source of genetic variations in HIV, exhibits a widespread mRNA splicing defect in the Cercopithecinae subfamily, which includes the commonly used NHP models.

A. Mendez, Rachael Springman-Rodriguez, Ayub Bokani et al. · 0 citations
Review Open access Aug 2026

Intra-Host Evolution of SARS-CoV-2 During Persistent Infection of Pediatric COVID-19 Patients

Clinical characteristics and intra-host viral evolution in pediatric patients with prolonged COVID-19 are examined, comparing immunocompetent and immunocompromised hosts, highlighting the need for continued genomic surveillance in vulnerable pediatric populations.

Charlie R. Boyle, Tien Doan, Estefany Rios-Guzman et al. · 0 citations

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