Author

J. G. Mikkelsen

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

#gene editing Sep 2026

Prime editing of human hematopoietic stem cells for correction of GATA2 deficiency.

GATA2 (GATA binding protein 2) deficiency is a severe immunodeficiency caused by heterozygous variants in the gene encoding the transcription factor GATA2. Ex vivo gene editing of a patient's own CD34+ hematopoietic stem and progenitor cells (HSPCs) could provide curative treatment. However, current methods that rely o...

J. H. Wolff, T. W. Skov, S. R. Dorset et al. · Science Translational Medici... · 0 citations

Aug 2026

A genome-wide map of the genetic network in monocytes that regulates type I interferon induction by the cGAS-STING pathway.

Type I interferons (IFNs) are induced by pattern recognition receptors (PRRs) of the innate immune system to protect against foreign pathogens and malignant transformation, and their production must be tightly regulated to balance antiviral defense with tissue homeostasis. To define the genetic network that governs IFN...

E. A. Thomsen, Jian Zhao, Ryo Narita et al. · Science Signaling · 0 citations