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This review discusses medicinal chemistry approaches primarily targeting HDAC1/2, LSD1, and DNMT1, with emphasis on inhibitor classes, binding mechanisms, structural features, preclinical evidence, and translational limitations, and how a better understanding of γ-globin repression may guide the development of safer an...
The convergence of AI and nanotechnology is revolutionizing healthcare by providing more accurate diagnostics, tailored treatments, and improved safety evaluations, and AI-driven models enhance drug discovery, optimize delivery systems, and strengthen toxicological assessments.
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