Review
Sep 2026
Tutorial: interrogating biology using organoid technologies.
J. Bugter, Simon T. Schafer, Roland Rad
· Nature Protocols · 0 citations
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Mutation-induced phenotypic plasticity drives formation of a pro-metastatic tumour-intrinsic niche
It is argued that formation of a tumour-intrinsic niche is a prerequisite for BRAF-mutant CRC seeding to distant organs and that interference with niche formation may help avoid metastatic relapse.
J. Bugter, L. El Bouazzaoui, E. Küçükköse et al.
· bioRxiv · 2 citations