Open access
Jul 2026
Variant-specific and cross-reactive antibody responses following COVID-19 booster vaccinations and SARS-CoV-2 breakthrough infections.
Depletion experiments revealed that booster-induced immunity was predominantly mediated by cross-reactive antibodies, with the highest levels after breakthrough infections and the lowest after a primary WT infection, providing functional insights into the antibody specificities associated with imprinting effects following variant-adapted booster vaccination.
Iris Medits-Weiss, Dominik Moll, D. Springer et al.
· Scientific Reports · 0 citations