Hui Fang

Germline BRCA1 Mutation Deregulates Irradiation–Induced Cell Cycle Checkpoints in Human Mammary Luminal Progenitors

A lineage-resolved monolayer culture system is established that enables propagation of primary human mammary epithelial populations while preserving lineage identity across passages and provides a functional framework for determining critical events in the expansion of genomically altered mammary epithelial cells in th...