Author

Huaji Qiu

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Open access Sep 2026

FAM134B Restricts African Swine Fever Virus Capsid Assembly via Reticulophagy and Its Antiviral Activity is Antagonized by the Viral Virulence‐Associated Factor pMGF300‐2R

ABSTRACT African swine fever (ASF), caused by African swine fever virus (ASFV), is a devastating viral disease in domestic pigs and wild boar. ASFV is a large DNA virus whose capsid assembly takes place within perinuclear viral factories (VFs). Accumulating evidence has demonstrated that reticulophagy confers antiviral...

Rui Luo, Jing Zhang, Ruojia Huang et al. · Advancement of science · 0 citations

Open access Aug 2026

A Recombinant Pseudorabies Virus Expressing Classical Swine Fever Virus (CSFV) E2 Protein Confers Complete Protection Against Lethal CSFV Challenge via Needle-Free Immunization

It is demonstrated that needle-free delivery of rPRVTJ-UL44-E2 confers complete protection against lethal CSFV challenge in pigs via needle-free immunization.

Ruojia Huang, Qiang Yang, Cao-Yuan Ma et al. · Vaccines · 0 citations

Open access Aug 2026

A CHO-Expressed Pseudorabies Virus gD Subunit Vaccine Elicits Potent Neutralizing Antibodies and Confers Complete Protection Against Lethal Challenge in Mice

The CHO cell-derived PRV gD subunit vaccine elicits robust humoral immune responses and provides complete protection against lethal PRV variant challenge in mice, and support its further evaluation in the natural swine host toward the development of a safe and scalable subunit vaccine for pseudorabies control.

Cao-Yuan Ma, Jia Li, Xin Song et al. · Vaccines · 0 citations

Aug 2026

[Construction and characterization of a stable Cas9-expressing monoclonal WSL cell line].

The generation of a WSL-Cas9 monoclonal cell line with high CRISPR/Cas9 editing efficiency, stable proliferation, and permissiveness for robust ASFV replication is reported, providing a reliable platform for future genome-wide functional screening to systematically identify host factors governing ASFV entry.

Meng Yao, Tianlong Li, Bin Sun et al. · Sheng wu gong cheng xue bao... · 0 citations