Esophageal Cancer: Molecular Biology/Pathology
Comparative genomic hybridization (CGH) method has contributed to the analysis of amplification and deletion of various genes. We detected Denticleless E3 ubiquitin protein ligase homolog (DTL) using the Agilent 244k oligo-array CGH and FISH analyses for 1q32...
Masateru Yamauchi, Shuhei Komatsu, Keiji Nishibeppu et al.· Diseases of the esophagus· 0 citations
Esophageal Cancer: Molecular Biology/Pathology
Replication factor C (activator 1) 3 (RFC3), located on 13q13.2, is reported to be necessary for the elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon. In this study, we tested whether RFC3 acts as a cancer-promoting factor...
Hiroyuki Kanazawa, Shuhei Komatsu, Jun Kiuchi et al.· Diseases of the esophagus· 0 citations
Esophageal Cancer: Molecular Biology/Pathology
Low levels of circulating tumor-suppressor microRNAs are associated with cancer progression and poor prognosis. However, their role in immune evasion and response to immune checkpoint inhibitors (ICIs) remains unclear.
We aimed to identify a PD-L1–targe...
Ryo Ishida, Shuhei Komatsu, Hajime Kamiya et al.· Diseases of the esophagus· 0 citations
Low levels of circulating tumor-suppressor microRNAs are associated with cancer progression and poor prognosis. However, their role in immune evasion and response to immune checkpoint inhibitors (ICIs) remains unclear. We aimed to identify a PD-L1-targeting tumor-suppressor microRNA downregulated in esophageal squamous...
