The development and drug resistance of breast cancer are closely associated with the heterogeneity of the tumor microenvironment (TME). Immunosuppressive cells, activated matrix components, abnormal vascular networks, and metabolic reprogramming within the TME collectively create a niche that promotes tumor survival. D...
Yan-Cai Liu, Yan-Ran Yang, Jiang-Long Wang et al.· Natural Products and Biopros...· 0 citations
This motif may serve as a reference for the selection and evaluation of diagnostic antibodies targeting conserved regions of the SARS-CoV-2 N protein and show that this sequence is conserved among the representative SARS-CoV-2 lineages analyzed.
Zhoujun Su, Junhao Guo, Ning Li et al.· Viruses· 0 citations
The results provide an epitope-level explanation for the sustained diagnostic reliability of the mAb N179-based assay against emerging variants, clarify the molecular basis for its lack of cross-reactivity, and may inform the rational design of SARS-CoV-2 diagnostics targeting conserved, mutation-resistant epitopes.
Zhoujun Su, Junhao Guo, He-Feng Zhou et al.· bioRxiv· 0 citations
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