Author

Hasan Uludağ

2 papers indexed here

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Open access 2026

Targeted NLRP3 Silencing with Lipopolymer Nanocarriers for Precision Therapy in IL-1β-Mediated Autoinflammatory Diseases

Objectives. Inflammatory diseases could arise from dysregulated innate immunity, often driven by pathogenic activation of the NLRP3 inflammasome, which promotes caspase-1-mediated maturation and secretion of interleukin-1β (IL-1β). While IL-1-blocking biologics...

Mohammad Nasrullah, A. Rajendran, K. C. Bahadur Remant et al. · RSC Pharmaceutics · 0 citations

#gene editing Open access Sep 2026

Charge modulation of peptide/nucleic acid complexes: an anionic additive enhances gene silencing and CRISPR/Cas9 editing by promoting intracellular nucleic acid release

Small interfering RNA (siRNA) and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated Protein 9 (Cas9) complexes are effective approaches to temporarily downregulate protein expression via post-transcription RNA interference or permanently altering protein expression via editing gen...

Abdulelah Alhazza, Sorour Khayyatnejad Shoushtari, Hasan Uludağ et al. · Frontiers in Nanotechnology · 0 citations