Single-cell transcriptomic profiling of cerebrospinal fluid reveals immune-cell heterogeneity and multicompartment MIF/CD74-related communication in tuberculous and purulent meningitis
The findings highlight substantial inter-individual heterogeneity, broad innate immune-cell patterns, overlapping CD4+ T-cell transcriptional states, and multicompartment MIF/CD74-related communication in both TBM and purulent meningitis.