A central challenge in de novo protein design is generating proteins with desired structural and functional properties. Existing design models typically require a dedicated input representation for each property, limiting the design objectives they support. We develop Prompteina, the first all-atom structure generation...
Joseph Lee, Yan-Jing Li, Bo Qiang et al.· 1 citation
An extensive evaluation of automatic harness evolution for LLM agents is conducted, comparing harness evolution with simple test-time scaling and discovery baselines under comparable feedback and inference budgets, and also evaluating evolved harnesses on held-out tasks to assess whether the discovered improvements gen...
Yike Wang, Huaisheng Zhu, Zhengyu Hu et al.· arXiv.org· 18 citations
FLIP (FLipped Inference for Prompt reconstruction), a reference-free and rubric-free reward modeling approach that reformulates reward modeling through backward inference that enables reliable reward modeling in downscaled regimes where judgment methods fail, is proposed.
This work demonstrates the importance of estimating whether poison injections are included in pretraining data, and establishes third-party webpage content as a possible vector for attacking language model pretraining.
Victoria Graf, Hanna Hajishirzi, Noah A. Smith et al.· 0 citations
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