Background In this study, the potential protective effects of adenosine triphosphate (ATP) and glutathione (GSH) against atezolizumab-induced cardiac injury in rat heart tissue were investigated. Methods A total of 24 male albino Wistar rats were used in the experiment. The animals were divided into four groups: health...
Yeşim Kaya Yaşar, Esra Tuba Sezgin, B. Suleyman et al.· Frontiers in Pharmacology· 0 citations
Pembrolizumab, an immune checkpoint inhibitor targeting programmed cell death protein-1 (PD-1), has substantially improved cancer treatment outcomes but may induce immune-related cardiotoxicity characterized by oxidative stress, inflammation, and apoptosis. Trimetazidine is a metabolic modulator with antioxidant and...
Ozlem Admis, Esra Tuba Sezgin, M. Ozkaraca et al.· Scientific Reports· 0 citations
Ovarian ischemia/reperfusion (I/R) injury is a major cause of tissue damage following the surgical detorsion of ovarian torsion and is characterized by excessive oxidative stress, inflammation, and progressive cellular injury. Although ranolazine has been reported to exert antioxidant and anti-inflammatory effects in v...
Mesut Admış, Esra Tuba Sezgin, Z. Suleyman et al.· International Journal of Mol...· 0 citations
Centella asiatica demonstrates significant potential in mitigating DOX-induced oxidative damage, attenuating testicular injury and preserving the functional integrity of the male reproductive system.
F. Bedir, Z. Suleyman, H. Kocaturk et al.· International Journal of Mol...· 0 citations
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