The Id2 induced block in T cell generation is overcome by TCR ab overexpression
It is shown that sustained Notch induced signals are required to seal the commitment of TCR ab /CD3 expressing cells into the TCR ab T cell lineage, which otherwise develop into cells phenotypically resembling NK cells or NKT cells.
A. V. van Lent, B. Blom, M. Nagasawa et al.
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