AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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It is hypothesize that slide helix position in the membrane might possibly act as a "conformational switch" in regulating the KirBac1.1 function, and results involving dynamic lipid-protein interactions in lipid-dependent gating might be relevant for other Kir channels.
The binding sites of the channel for various ligands/modulators are highlighted, and an emerging model focusing on the structural rearrangements associated with the transition of the channel from the closed/deactivated to open/activated conformation during lipid-dependent gating is provided which should be broadly appl...
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