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Author

H. Brenner

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#protein folding Open access Oct 2026

Systemic Inflammation and Colorectal Cancer: Assessing the Role of Reverse Causality

Background/Objectives: Prospective studies have reported associations between systemic inflammatory biomarkers and colorectal cancer (CRC) risk, but whether these reflect a causal role of inflammation or responses to preclinical disease remains uncertain. Methods: Using data from 383,850 UK Biobank participants (aged 4...

F. Safizadeh, T. Gwenzi, Marko Mandic et al. · 0 citations
Open access Jul 2026

Age- and sex-dependent associations of metabolic syndrome with colorectal cancer in the UK Biobank.

BACKGROUND The concurrent rise in metabolic syndrome (MetS) and the changing age profile of colorectal cancer (CRC) necessitates clarifying the heterogeneity in their association across demographic groups. This study aimed to define the precise age- and sex-specific associations between MetS and CRC risk, addressing a...

Zi-Lin Luo, F. Safizadeh, Marko Mandic et al. · 0 citations
Open access Jul 2026

Predictive value of plasma p-tau217 for Alzheimer’s dementia compared to other blood-based biomarkers

P-tau217, NfL and GFAP showed strong associations with AD risk, especially within the first 9 years of follow-up, outperforming p-tau181, and over the later years of follow-up, the predictive accuracy of p-tau217 was significantly reduced.

K. Trares, D. Duman, L. Beyer et al. · 0 citations

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