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Guan-Heng Zhu

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#gene editing Sep 2026

Targeting DOPA decarboxylase disrupts immune-metabolic coordination and renders Spodoptera frugiperda susceptible to bacterial infection.

DOPA decarboxylase (DDC) is a key enzyme that connects melanin production and innate immunity in insects, yet its regulatory network in major lepidopteran pests remains poorly understood. We combined CRISPR/Cas9 gene editing with multi-omics analysis to explore DDC's role in immune responses in the invasive pest Spodop...

Ze-Yuan Zhang, Shang-Huan Huang, Shen-Lei Li et al. · 0 citations

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