The common marmoset is a New World monkey (NWM) commonly used as a model organism to investigate questions in primate evolution and human disease, including Alzheimer’s and other neurodegenerative diseases, as well as neuropsychiatric disorders. Here we present the first telomere-to-telomere (T2T) reference genome for...
Prajna Hebbar, Tamara A. Potapova, Hailey Loucks et al.· bioRxiv· 0 citations
AppSAA mice recapitulate age-dependent, human-relevant AD phenotypes with defined therapeutic windows for preclinical research and is available without restriction from The Jackson Laboratory.
Lucy J. Sloan, Dylan T. Garceau, Nick J. Ryan et al.· bioRxiv· 0 citations
Using human induced pluripotent stem cells (hiPSCs)‐derived neurons, human induced pluripotent stem cells were assayed how reducing gene expression of MSN and CD44 affected amyloid beta secretion, tau phosphorylation, and transcriptional state.
Eiden H. Brewer, Charles A. Williams, Gregory A. Cary et al.· Alzheimer's & Dementia· 0 citations
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