How advances in large DNA assembly, synthetic biology, and genome-wide validation are making chromosome-scale genome engineering an increasingly tractable experimental framework for understanding, building, and repairing genomes is discussed, while outlining the analytical requirements and current technical barriers th...
Miriam Saponaro, Pierre Murat, Francesca Agostini et al.· Trends in Genetics· 0 citations
Head/neck melanoma showed higher frequencies of the rs11549465 CC genotype combined with obesity and several smoking-related exposures than melanomas at other sites and healthy controls, and these findings should be considered exploratory.
C. Buligan, Vincenzo Maione, Gianluca Petris et al.· Cancers· 1 citation
The genotype and allele frequencies of the interleukin-1β gene (IL-1B) promoter polymorphism rs16944 (-511, C > T) in cutaneous melanoma patients and healthy controls from Northeastern Italy revealed a possible candidate marker associated with melanoma susceptibility, Stage IV status, and lower-extremity localization.
S. Cauci, C. Buligan, Patrizia Nacci et al.· Current Oncology· 1 citation
Preliminary findings suggest a possible association between IL1B rs1143634 T allele carriage and cutaneous melanoma susceptibility in this cohort, and the Stage IV and upper-limb observations should be considered hypothesis-generating.
S. Cauci, C. Buligan, Luca Bazzichetto et al.· Genes· 2 citations
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